The most impactful changes to Native American populations done by the colonial settlement was:
1 - the disease - smallpox and influenza killed almost 90% American Native population 2. extermination policies - by hunting them, the population was in decline3. Territory - the colonists took their land4. forced relocation policies - the colonits forced them to stay in some special place, no leaving, starving them5. coexistence reasoning - the differences between colonist and Native believes