Gluconeogenesis is a process that produces glucose from non-carbohydrate sources.
When our body has to go too many hours without eating, gluconeogenesis starts. The first source to be consumed is: glycogen- the way our body storages glucose when there's too many of it. After that the fats and proteins will be consumed to go to this process.
It's always necessary to have a supply of glucose because the ONLY source of energy our neurons can take is glucose. without glucose our brains will shut down and can be fatal if not treated in time, making it the worst danger of the prolonged gluconeogenesis.