Intestinal epithelial cells (IECs), which line the surface of the intestinal epithelium, are crucial for food digestion, nutrient absorption, and the body's defence against infections from microbes, among other functions.
Diseases can be brought on by IEC dysfunction. Epithelial cells, which make up the mucosa, secrete mucus, a viscous fluid that acts as a barrier. The mucosa's primary jobs include absorbing and transporting nutrients, maintaining tissue moisture, and guarding the body against viruses and external objects.
Intercellular junctional complexes form a monolayer that firmly holds IECs together. The characteristics and processes of the intestinal epithelial barrier are primarily determined by tight junctions.
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