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Review the concept of colinearity and consider the following question: Certain mutations called amber in bacteria and viruses result in premature termination of polypeptide chains during translation. Many amber mutations have been detected at different points along the gene that codes for a head protein in phage T4. How might this system be further investigated to demonstrate and support the concept of colinearity

Respuesta :

The nearer to the initiation site the amber mutation occurs, the shorter the resulting polypeptide.

An amber mutation is what?

A premature emergence of the terminator codon UAG in the mRNA results in a nonsense mutation, which results in the production of an ineffective protein.

Which host has given permission to the T4 phage's Amber mutant?

Using both permissive (su+) and nonpermissive (su+) Escherichia coli hosts, the growth characteristics of twelve distinct amber (am) mutations of the bacteriophage T4 gene 43 (DNA polymerase) were studied.

A T4 phage mutant is what kind of mutant?

  • By the 1950s, experts in phage genetics had discovered a particular mutation in the T4 bacteriophage known as r (for rapid), which made the phage kill bacteria more fast than usual.

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