Answer:
the image is the first part of the Q
Explanation:
its because function is determined by shape, so whenever the shape changes the function of the receptor or the polypeptide chain changes. Where maybe the structural change might change the folding and the binding of the molecule in the next levels of protein structure. maybe it will turn the structure into hydrophobic(nonpolar, uncharged) or hydrophilic(ionic, charged). or maybe the whole thing about the structural change have distributed the receptor from functioning probably....there are many ways that amino acid substitution would affect the functioning of the protein. depending on the amino acids that they were replaced by the original one can determine the way that the receptor have to function by the surrounding environment.
