An 86 year old female patient who was being treated with vancomycin for a staph infection of a knee prosthesis. The usual dose of vancomycin is 500mg every 12 hr .Her weight was 64.3 kg, height 165 cm, with UN stable serum creatinine of 2.9 mg/dl.
What do you suggest to do for this patient?.
Does the patient immediately need a modified dose?