Suppose a mutation changes the amino acid that an aminoacyl-tRNA synthetase enzyme recognizes without changing the tRNA molecule that it recognizes. How is this likely to affect the process of protein synthesis? Check all that apply.

1.It will alter the location of the start sites during transcription
2.It will alter the sequence of bases in the mature mRNAs
3.It will alter the location of splice sites in the pre-mRNAs
4.It will alter the location of the start codons during translation
5.It will alter the sequence of amino acids in the polypeptide chains
6.It will cause premature termination of translation, resulting in shortened polypeptide chains
7.It will affect the synthesis of only one or a few types of protein produced by the cell
8.It will affect the synthesis of most or all of the proteins produced by the cell