Propanone is more soluble in water compared to propane mainly because propanone cannot hydrogen bond with themselves but can hydrogen bond with water molecules. One of the slightly positive hydrogen atoms in a water molecule can be sufficiently attracted to one of the lone pairs on the oxygen atom of propanone. In order for 3-hexanol to bond with water, the van der Waals forces must be broken and also the stronger hydrogen bonds of water molecules and it needs a great amount of energy.
