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__________ is caused by a genetic mutation that results in the production of abnormal hemoglobin. Under low-oxygen conditions, the abnormal beta chains link together and form stiff rods that alter the shape of the RBCs. thalassemia sickle-cell anemia polycythemia Leukopenia

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annyksl

Answer:

Thalassemia

Explanation:

Thalassemia, also known as Mediterranean anemia, is an inherited disease brought to Brazil by the inhabitants of countries bordering the Mediterranean Sea. Its main feature is the abnormal production of hemoglobin, a blood protein responsible for transporting oxygen to all body tissues.

The symptoms of thalassemia are directly related to the severity of the disease. The most common are:

  • Tiredness and weakness;
  • Pallor and jaundice;
  • Delayed growth;
  • Developed abdomen;
  • Enlargement of the spleen;
  • Bone changes.

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