Advantages:
Enhance protein digestion. The addition of a protease to a feed can result in improved amino acid digestibility across various protein sources. Minimize the impact of anti-nutritional factors.
Disadvantages:
Enzymes can be denatured by even a small increase in temperature. They are also susceptible to poisons and changes in pH. This means the conditions they work in must be tightly controlled
Enzymes can be expensive to produce
Contamination of the enzyme with other substances can affect the reaction.
Hope it helps!