In humans, red blood cells lose their nuclei in the process of maturation. The loss of this organelle has several functional consequences. Select all the correct statements below:
A) Red blood cells are unable to replicate or repair damaged DNA due to the absence of a nucleus.
B) The lack of a nucleus allows red blood cells to carry more oxygen by increasing their surface area-to-volume ratio.
C) Without a nucleus, red blood cells have a shorter lifespan compared to cells with nuclei.
D) The absence of a nucleus in red blood cells makes them more flexible, enabling them to squeeze through narrow capillaries.